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Lacking management of laboratory equipment in university currently, a strategy was proposed to manage laboratory equipment with network method by using software architecture based on C/S and B/S model. Network management platform for experimental equipment is a management system, which is also a complex monitoring system. For different users, being designed by reasonable software architecture, it will make better prospects for the system. This paper presents a framework of laboratory equipment management system of hybrid system, which includes the realization of main function, architecture, database design and implementation.