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In this paper, we investigate how MapReduce and Cloud computing can accelerate performance of applications and scale up the computing resources through a real data mining use case in the Biomedical Sciences. We have prototyped the data mining task using the MapReduce model and evaluated it in the Cloud. A performance evaluation model has been built for assessing the eff ciency of the prototype. The results, from both experiments and the evaluation model, show the performance and scalability can be enhanced through these advanced technologies.