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Data mining deepens the data analysis, also is able to mine the interesting mode hiding in mass data automatically. As a new data analysis technology, data mining makes full use of the modern software technology and computer scientific knowledge, has the extremely important research significance, provides for researchers of various fields with a new intelligence means to realize and use data. In data mining, association rule learning is a popular and well researched method for discovering interesting relations between variables in large databases. This paper makes a series of data analysis and research on the application of data mining technology in the students' scores. This paper use Apriori algorithm of association rules to analyze the intrinsic link among various courses, dig out the precedence relationship and association of students' learning courses, reveal the teaching regularities and problems from large amount of data, as well as to provide a strong basis for reasonable course-setting.