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Contrast-enhanced ultrasound (CEUS) has demonstrated utility in the monitoring of blood flow in tissues, organs, and tumors. Current CEUS methods typically provide only relative image-derived measurements, rather than quantitative values of blood flow in milliliters/minute per gram of tissue. The purpose of this study is to validate CEUS-derived measurements of renal blood flow (RBF) with absolute values of ml/min per gram of tissue based on a calibrated flow probe. New information about the effects of parameters such as contrast agent administration rate and transducer positioning on two different image-derived measurements are provided.
Ultrasonics Symposium (IUS), 2011 IEEE International
Date of Conference: 18-21 Oct. 2011