By Topic

Investigation on the Influence of T-2 Toxin on the Ameloblasts in Rat's Incisor

Sign In

Cookies must be enabled to login.After enabling cookies , please use refresh or reload or ctrl+f5 on the browser for the login options.

Formats Non-Member Member
$33 $13
Learn how you can qualify for the best price for this item!
Become an IEEE Member or Subscribe to
IEEE Xplore for exclusive pricing!
close button

puzzle piece

IEEE membership options for an individual and IEEE Xplore subscriptions for an organization offer the most affordable access to essential journal articles, conference papers, standards, eBooks, and eLearning courses.

Learn more about:

IEEE membership

IEEE Xplore subscriptions

3 Author(s)
Sha-fei Zhai ; Oral medicine dept.of Xian medical university, Xi'an medical university, China ; Zhu Yong ; Yao-chao Zhang

T-2 toxin, which belongs to a group of mycotoxins synthesized by Fusarium fungi that are widely encountered as natural contaminants, induced enamel and ameloblasts damage in rats. SD rats were randomly divided into three groups and received gavages containing T-2 toxin in a dosage of 0, 100, and 200ng/g b.w., respectively. After 4 weeks, all rats were killed, serial sections along the long axis and HE method was used to stain ameloblast. In visual inspection, incisor color changed into faint yellow, part region showed light-proof and the tooth surface was a little rough in the poisoned groups. Under the Microscope, Tome's process of the ameloblasts disappeared and distorted and vacuolated ameloblasts existed in poisoned groups. The high-dose T-2 toxin group was more serious. This is the first report that T-2 toxin affects the cell morphology of ameloblasts and induces the appearance changes in tooth organ.

Published in:

Information Technology in Medicine and Education (ITME), 2012 International Symposium on  (Volume:2 )

Date of Conference:

3-5 Aug. 2012