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The use of the ALOPEX process in extracting normal and abnormal visual evoked potentials

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2 Author(s)
Wang, J.-Z. ; Dept. of Biomed. Eng., Rutgers Univ., Piscataway, NJ, USA ; Micheli-Tzanakou, E.

The ALOPEX method, a multiparameter stochastic optimization technique, is used for the optimal extraction of parameters in fitting randomly chosen action potentials to normal and abnormal visual evoked potential (VEP) waveforms. It is assumed that conformational changes in the abnormal VEPs can be attributed to an asynchrony in the arrival of action potentials at an integration point in the visual cortex. The results indicate that the assumption is valid in all five of the five records processed, of which two were normal and three abnormal. Further experimentation is needed to see if the method can be used as a diagnostic tool.<>

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Engineering in Medicine and Biology Magazine, IEEE  (Volume:9 ,  Issue: 1 )