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We propose a transcription on graphs of recent continuous global active contours proposed for image segmentation to address the problem of binary partitioning of data represented by graphs. To do so, using the framework of Partial difference Equations (PdEs), we propose a family of nonlocal regularization functionals that verify the co-area formula on graphs. The gradients of a sub-graph are introduced and their properties studied. Relations, for the case of a sub-graph, between the introduced nonlocal regularization functionals and nonlocal discrete perimeters are exhibited and the co-area formula on graphs is introduced. Finally, nonlocal global minimizers can be considered on graphs with the associated energies. Experiments show the benefits of the approach for nonlocal image segmentation and high dimensional data clustering.