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In this paper, we present system design of remote data recording for epileptic and stroke patients. We report wireless recording system combining near infra-red spectrometry (NIRS) in a comprehensive non-invasive evaluation and both electroencephalographic (EEG), and intracerebral EEG (icEEG) recording in presurgical evaluation. A Bluetooth and dual radio links were introduced for these recording. The Bluetooth-based device was embedded in a non-invasive multichannel EEG-NIRS system for easy portability and long term monitoring. On the other hand, the recorded icEEG signals from up to 128 channels through intracerebral electrodes are transmitted wirelessly to a remote base station. This transmitter front-end contains preamplifier, proper filtering, data converter and power amplifier. The RF back-end is based on commercial transceiver operated in the Medical Implant Communication Service (MICS) 400 MHz band. Power consumption of the front-end and transmitter are 0.75mW and 15mW, respectively. The proposed remote monitoring systems are validated in vitro using data recording from human patients.