Cart (Loading....) | Create Account
Close category search window
 

Gene regulatory network model identification using artificial bee colony and swarm intelligence

Sign In

Cookies must be enabled to login.After enabling cookies , please use refresh or reload or ctrl+f5 on the browser for the login options.

Formats Non-Member Member
$31 $13
Learn how you can qualify for the best price for this item!
Become an IEEE Member or Subscribe to
IEEE Xplore for exclusive pricing!
close button

puzzle piece

IEEE membership options for an individual and IEEE Xplore subscriptions for an organization offer the most affordable access to essential journal articles, conference papers, standards, eBooks, and eLearning courses.

Learn more about:

IEEE membership

IEEE Xplore subscriptions

3 Author(s)
Forghany, Z. ; Gorlaeus Lab., Leiden Univ., Leiden, Netherlands ; Davarynejad, M. ; Snaar-Jagalska, B.E.

Gene association/interaction networks have complex structures that provide a better understanding of mechanisms at the molecular level that govern essential processes inside the cell. The interaction mechanisms are conventionally modeled by nonlinear dynamic systems of coupled differential equations (S-systems) adhering to the power-law formalism. Our implementation adopts an S-system that is rich enough in structure to capture the dynamics of the gene regulatory networks (GRN) of interest. A comparison of three widely used population-based techniques, namely evolutionary algorithms (EAs), local best particle swarm optimization (PSO) with random topology, and artificial bee colony (ABC) are performed in this study to rapidly identify a solution to inverse problem of GRN reconstruction for understanding the dynamics of the underlying system. A simple yet effective modification of the ABC algorithm, shortly ABC* is proposed as well and tested on the GRN problem. Simulation results on two small-size and a medium size hypothetical gene regulatory networks confirms that the proposed ABC* is superior to all other search schemes studied here.

Published in:

Evolutionary Computation (CEC), 2012 IEEE Congress on

Date of Conference:

10-15 June 2012

Need Help?


IEEE Advancing Technology for Humanity About IEEE Xplore | Contact | Help | Terms of Use | Nondiscrimination Policy | Site Map | Privacy & Opting Out of Cookies

A not-for-profit organization, IEEE is the world's largest professional association for the advancement of technology.
© Copyright 2014 IEEE - All rights reserved. Use of this web site signifies your agreement to the terms and conditions.