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A Method to Resolve Weak and Overlapping Signals in Proton Magnetic Resonance Spectroscopy

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3 Author(s)
Jiang Gang ; Sch. of Phys. & Technol., Wuhan Univ., Wuhan, China ; Quan Hong ; Wang Cheng

In this paper a new method of combining translation invariant (TI) and wavelet-threshold (WT) algorithm to resolve overlapping signals in proton magnetic resonance spectroscopy (1H-MRS) is presented. First, the 1H-MRS spectrum signal was transformed into wavelet domain and its wavelet coefficients were obtained, Then, the translation invariant (TI) method and wavelet-threshold (WT) method were applied to separate the weak signals overlapped with the strong ones, Analysis of the simulation and in vivo data with this method has showed that weak signals could be obtained accurately and further the peak area of weak signals could be quantitatively calculated if combined with signal fitting.

Published in:

Biomedical Engineering and Biotechnology (iCBEB), 2012 International Conference on

Date of Conference:

28-30 May 2012