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Increasing popularity of the notion of service in the enterprise applications development leads to the new types of inter-organizational collaborations. We can observe a shift in this collaboration from simple exchange of services to the co-creation of transdisciplinary services offering a new and unique value to the involved partners. In this paper we define the notion of transdisciplinary information service and we discuss the main principles, namely communication, collaboration, co-innovation, and agility, to be considered in the transdisciplinary information services co-creation and we identify the existing approaches and techniques that support the implementation of these principles. Finally, we introduce our proposal for the elaboration of a method family supporting the co-creation of transdisciplinary information services. This method family aims to provide a flexible and agile process model based on transdisciplinarity principles and allowing to combine method chunks from different disciplines in order to support collaborative creativity, modeling and development of transdisciplinary services.