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The need for a non-intrusive evaluation infrastructure platform to support research on reliable pervasive healthcare in the unsupervised setting is analyzed and challenges and possibilities are identified. A list of requirements is presented and a solution is suggested that would allow researchers to more easily build and evaluate prototypes for measuring and quantifying the use-context of patients using current state-of-the-art biomedical devices in the unsupervised setting. An initial implementation is introduced as the reliable evaluation infrastructure (RELEI) platform. Several research prototypes using the basic RELEI platform are presented to illustrate the purpose, and provide experiences on platform usage.