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Carrier Aggregation (CA) adds a new scheduling domain which makes the radio resource management more flexible for future LTE-Advanced system, and also provides a new path to solve the intra-tier interference among femtocells. This paper proposes a Cooperative Power Setting Scheme to mitigate the intra-tier interference among CA-based femtocells. In the proposed scheme the impact of transmission power is considered, and femtocells cooperatively adjust their transmission power to optimize the total throughput on each Component Carrier. Simulation proves that the proposed scheme is effective and compensates for the deficiency of existing researches. The advantage of the proposed scheme is obvious especially when the deployment of femtocells is dense.