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Development and integration of physiological sensors into automotive applications is gaining importance. Assistance systems which possess knowledge about the driver's cognitive state could increase road safety. In this paper we present a flexible framework that enables the development, evaluation and verification of sensors and algorithms for automotive applications using physiological signals under realistic driving conditions. We have integrated a custom capacitive ECG measurement system into a test car and validated its performance in real world driving tests. During first test runs, the capacitive system achieved a sensitivity of up to 95.5% and a precision rate of up to 92.6%. Our system also records synchronized vehicle dynamics. We discuss the road test measurements which suggest that the driving situation highly impacts the quality of ECG signal. Therefore, information on driving dynamics could be used to improve the precision rate of future capacitive ECG measurement.