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According to the current domestic regional medical information construction situation, the construction thinking of medical information collaborative service platform is presented in this paper. On the basis of the data in hospital information system, centralized and distributed storage are combined, regional collaborative medical data centers are established to achieve integration among hospital information. Then, the interaction interface between hospital information system and collaborative medical data center through Web Service are set up. Therefore, the platform possesses modularization and extensibility. In the meantime, the system stability and usability are increased.