By Topic

Evaluation of Thermal and Nonthermal Effects of UHF RFID Exposure on Biological Drugs

Sign In

Cookies must be enabled to login.After enabling cookies , please use refresh or reload or ctrl+f5 on the browser for the login options.

Formats Non-Member Member
$33 $13
Learn how you can qualify for the best price for this item!
Become an IEEE Member or Subscribe to
IEEE Xplore for exclusive pricing!
close button

puzzle piece

IEEE membership options for an individual and IEEE Xplore subscriptions for an organization offer the most affordable access to essential journal articles, conference papers, standards, eBooks, and eLearning courses.

Learn more about:

IEEE membership

IEEE Xplore subscriptions

7 Author(s)
Giovanni Calcagnini ; Department of Technology and Health , Italian National Institute of Health, Rome, Italy ; Federica Censi ; Michele Maffia ; Luca Mainetti
more authors

The radio frequency identification (RFID) technology promises to improve several processes in the healthcare scenario, especially those related to the traceability of people and things. Unfortunately, there are still some barriers limiting the large-scale deployment of these innovative technologies in the healthcare field. Among these, the evaluation of potential thermal and nonthermal effects due to the exposure of biopharmaceutical products to electromagnetic fields is very challenging, but still slightly investigated. This paper aims to setup a controlled RF exposure environment, in order to reproduce a worst case exposure of pharmaceutical products to the electromagnetic fields generated by the UHF RFID devices placed along the supply chain. Radiated powers several times higher than recommended by current normative limits were applied (10 and 20 W). The electric field strength at the exposed sample location, used in tests, was as high as 100 V/m. Nonthermal effects were evaluated by chromatography techniques and in vitro assays. The results obtained for a particular case study, the ActrapidTM human insulin preparation, showed temperature increases lower than 0.5 °C and no significant changes in the structure and performance of the considered drug.

Published in:

IEEE Transactions on Information Technology in Biomedicine  (Volume:16 ,  Issue: 6 )
IEEE RFID Virtual Journal