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The infrastructureless nature of communication in Mobile Ad hoc NETworks (MANET) pose many challenges to the researchers in terms of improving the reliability within the constraints of limited resources. Most of the performance measures and evaluation on different protocols in various network conditions proved the trustworthiness of the routing schemes as well as their limitations. In the present investigation, a statistical analysis of the simulated network characteristics was performed using response surface method for a possible prediction of the influence of network conditions on the response variables by using AODV and its multi-path variant AOMDV as the routing protocol. The mobility and workload was primarily varied at different levels and the responses such as throughput and end-to-end delay was measured. The optimization of the given input data provided a clear understanding of the effect of mobility and workload on the response variables.