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Numerical processing of passive UHF-RFID tags' response may provide physical insight about the hosting object or about the nearby environment. This idea is here extended to implanted antennas with the purpose to sense the evolution of some human physiological and pathological process involving a local change of effective permittivity inside the body. The goal is to understand how master the design of this class of devices taking into account both communication and sensing capabilities. An ad hoc design methodology is here presented and discussed by means of a realistic medical case concerning the modification of an endo-vascular device to achieve a STENTag able to sense the state of the vessel wherein it has been implanted.