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X-ray computed tomography devices and X-ray diffraction techniques are powerful tools: the former provide volumetric data of samples during a non-destructive examination for biology and material science, and the latter measure grain orientation and strain, as well as crystalline phase identification and structure refinement. Today, the European Synchrotron Radiation Facility (ESRF) provides increasingly higher energy beams, up to 150 keV combined with higher brilliance (1013 X-ray photons/sec). This means that detectors suffer from low X-ray absorption at high spatial resolution (1-10 μm) and from radiation damage in tomography and diffraction applications. In addition, more and more experiments in medicine require the absorbed dose by the sample to be reduced. In this context, more efficient scintillators are developed and evaluated at the ESRF. In order to perform sub-micrometer and micrometer resolution imaging scintillators 1 μm to 500 μm thin are required. Single Crystal Film scintillators (SCF), 1 μm to 100 μm can be obtained via Liquid Phase Epitaxy for sub-micrometer resolution. Transparent ceramics, 100 μm to 500 μm thick are promising candidates for X-ray imaging requiring high X-ray absorption and good contrast with micrometer resolution. Commonly available scintillators, such as CdWO4 and YAG:Ce suffer from low efficiency, therefore new scintillators with higher light yield and stopping-power are required. A first test was carried out to evaluate an Europium doped Lutetium Oxide ceramic for micrometer resolution and new SCFs of Lu3Ga5-xInxO12:Eu for sub-micrometer resolution are investigated. Performance of Lu2O3 and LuInGG, i.e absorption, light yield, afterglow, spatial resolution will be presented and compared to standard screens (YAG, GGG). First results will be illustrated with X-ray images and will demonst- ate the absorption efficiency improvement at high spatial resolution.