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This paper presents a new voltage-mode multiple-input multiple-output (MIMO) multifunction filter using five single-ended operational transconductance amplifiers (OTAs), two capacitors and one resistor. The proposed filter can provides low-pass, band-pass, high-pass, band-stop and all-pass voltage responses by appropriately connecting the input and output terminals. The natural frequency and the quality factor can be controlled orthogonally and electronically by adjusting the biasing currents of OTAs. Simulation results are also performed to confirm the theoretical analysis.