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Health Informatics Design for Assisted Diagnosis of Subclinical Atherosclerosis, Structural, and Functional Arterial Age Calculus and Patient-Specific Cardiovascular Risk Evaluation

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7 Author(s)
Santana, D.B. ; Physiol. Dept., Republic Univ., Montevideo, Uruguay ; Zocalo, Y.A. ; Ventura, I.F. ; Arrosa, J.F.T.
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Traditional methods used to assess cardiovascular risk (i.e., the Framingham Risk Score) exhibit clear limitations. To aid in patient-specific risk stratification and diagnosis it has been proposed to evaluate noninvasively structural and functional arterial parameters. A National Public University Center (CUiiDARTE) was created in Uruguay with the aim of developing and applying strategies to improve cardiovascular risk stratification and subclinical vascular disease detection. To this end a health informatics approach and tool was designed, developed, and implemented in CUiiDARTE. Its goals were to: 1) promote screening for subclinical atherosclerosis, 2) develop a centralized database to store information obtained noninvasively from anywhere in our country, 3) develop a biomathematical model integrating values for arterial structure and function into traditional cardiovascular risk assessment, 4) generate a detailed and comprehensive report for the specialist comparing patient data with reference data from the healthy population, 5) generate a similar report (using a structural and functional arterial age calculator) for the patients assessing the state of their arteries. In this paper, we present the main characteristics of the CUiiDARTE health informatics development.

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Information Technology in Biomedicine, IEEE Transactions on  (Volume:16 ,  Issue: 5 )