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The various codes are used for the error detection and correction in the field of communication. Some are for the single bit error and some are for the multiple bits error. Reed-Muller algorithm realizes the ability of multiple bits error detection and correction. With the superior error correction capability, these codes have initiated wide scale interests in satellite communication, wireless communication, and storage fields. Reed-Muller codes cover a wide range of service requirements and diverse interference conditions in wireless applications and can operate at both high and low code rates. In this paper, the comparison of Reed-Muller codes with different other codes for error detection and correction of multiple bits is proposed and further we can implement it on a Xilinx field programmable gate array (FPGA) device. Using Reed-Muller method the data is transferred from transmitter to receiver without any error. The error detection and correction principle and realization methods are described in detail. The multiple bits error detection and correction with Reed-Muller algorithm method can improve the bit error rate and packet error rate effectively.