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This paper presents low-invasive and low-power implantable biomedical devices based on a novel high-efficiency antenna for cloud health care. The proposed simple architecture was applied to fulfill a low-power consumption implantable system, including a readout circuit, an oscillator, a power management circuit, and an implantable antenna. This paper proposes a novel compact antenna for teeth implanting to attach on a low-invasive biomedical device to monitor human health conditions. A low-power consumption oscillator was connected directly to the antenna without any additional power amplifier. A hybrid of Archimedean spirals and Hilbert-based curve 3-D folded antenna was designed and fabricated on ceramic denture (ZrO2) in Medical Radio (MedRadio) band. A compact, high gain, and large bandwidth antenna was achieved. In addition, such simple architecture also performs a high precise measurement, demonstrated by the temperature sensing of basal body temperature (BBT), indicating the conditions of female endocrine abnormalities. High sensitivity was enhanced by a negative resistance sample amplifier, and the biological BBT signals were transmitted by a frequency-modulation transmitter. The wireless measurement results indicate a small error of ±0.058°C at a distance of 60 cm indoors, and satisfy the BBT resolution requirement of 0.1 °C.