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The goal of segmentation is to partition an image into disjoint regions. In this paper, the segmentation problem based on partition clustering is viewed as a combinatorial optimization problem. The original image is partitioned into small blocks by watershed algorithm, and the quantum-inspired immune clonal algorithm is used to search the optimal clustering centre, and make the sequence of maximum affinity function as clustering result, and finally obtain the segmentation result. Experimental results show that the proposed method is effective for SAR image segmentation.