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In this paper, we explore the spatial modulation (SM) orthogonal frequency division multiplexing (SM-OFDM) transmission to achieve good performance in Long Term Evolution (LTE) based systems. For assessment purposes, the performance results of SM-OFDM systems are compared with the popular Alamouti-coded OFDM systems and vertical Bell Labs layered space-time (V-BLAST) OFDM systems. Simulation results show that SM-OFDM systems achieve better performance than other systems at low spectral efficiencies. However, at high spectral efficiencies, the performance of SM depends on a trade-off between the spatial constellation size and signal constellation size. Furthermore, the results also show that SM provides a flexible transceiver configuration, especially for an unbalanced multiple-input multiple-output (MIMO) channel.