By Topic

Evaluation of windowed image reconstruction for time-of-flight PET

Sign In

Cookies must be enabled to login.After enabling cookies , please use refresh or reload or ctrl+f5 on the browser for the login options.

Formats Non-Member Member
$33 $13
Learn how you can qualify for the best price for this item!
Become an IEEE Member or Subscribe to
IEEE Xplore for exclusive pricing!
close button

puzzle piece

IEEE membership options for an individual and IEEE Xplore subscriptions for an organization offer the most affordable access to essential journal articles, conference papers, standards, eBooks, and eLearning courses.

Learn more about:

IEEE membership

IEEE Xplore subscriptions

3 Author(s)
Jinxia Guo ; Department of Biomedical Engineering, Huazhong University of Science and Technology, Wuhan, Hubei, China ; Chien-Min Kao ; Qinguo Xie

We have previously developed a windowed image reconstruction method that allows for region-of-interest (ROI) reconstruction from a subset of TOF PET data. As a result, the method may improve the reconstruction for a ROI by discarding data that are not particularly information-bearing to it but containing high statistical noise or unwanted events (scatter or random). In our previous paper, we have evaluated the performance of this method with numerical experiments and showed that it can improve the image signal-to-noise ratio (SNR) when considering only the true events. We also showed that it can recover the area near a high activity area better in comparison with the conventional filtered back-projection (FBP) algorithm for non-TOF PET and the convolved ramp and Gaussian with confidence weighting (CRG-CW) method for TOF-PET. In this work, we more extensively evaluate the performance of this windowed image reconstruction method by including also scatter and randoms in simulation. We evaluate the SNR of the reconstructed images in defined ROIs as well as the variations of the SNRs with the size of the window function. Our results indicate that the windowed image reconstruction method can generate images with higher SNRs relative to FBP images. In addition, when the ROI is small and nearby a high-activity structure, the windowed reconstruction method can generate better SNRs than do the CRG-CW method.

Published in:

Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC), 2011 IEEE

Date of Conference:

23-29 Oct. 2011