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This paper presents a concept of a novel breast cancer detection system based on fluorescence bioimaging (FBI) which consists of rare-earth-doped ceramic nanophosphors (RED-CNP) and near-infrared (NIR). The use of NIR light in the wavelength region between 800 and 2000 nm for biomedical photonics attracts great interests since the region is so-called “biological windows”, where biological tissues have minimal absorbance and also auto-fluorescence can be avoided. 3D measurement of breast cancer can be achieved by integrate NIR bioimaging which uses NIR emission under NIR excitation and laser light section method. In this paper, the 3D measurement experiments of an invisible object covered by chicken skin and meat are conducted. The experimental results suggest that the proposed method is useful for the 3D measurement breast cancer cell detection method.