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This Multi-parameter system was designed to monitor depth of Anaesthesia (DOA) for children surgical intervention. Three signals: ECG especially Heart rate variability (HRV) contained, Pressure of End-Tidal Carbon Dioxide (PETCO2) and Oxygen Saturation (SPO2) were used to evaluate depth of anaesthesia. Results show that the system can extract the signals clearly and reflect the change of signals feasible and reliable. The monitoring system can not only be used during the surgical, but also monitor the patient after surgical.