Cart (Loading....) | Create Account
Close category search window

Identifying Hub Proteins and Their Essentiality from Protein-protein Interaction Network

Sign In

Cookies must be enabled to login.After enabling cookies , please use refresh or reload or ctrl+f5 on the browser for the login options.

Formats Non-Member Member
$31 $13
Learn how you can qualify for the best price for this item!
Become an IEEE Member or Subscribe to
IEEE Xplore for exclusive pricing!
close button

puzzle piece

IEEE membership options for an individual and IEEE Xplore subscriptions for an organization offer the most affordable access to essential journal articles, conference papers, standards, eBooks, and eLearning courses.

Learn more about:

IEEE membership

IEEE Xplore subscriptions

3 Author(s)
Bakar, S.A. ; Centre for Distrib. & High Performance Comput., Univ. of Sydney, Sydney, NSW, Australia ; Taheri, J. ; Zomaya, A.Y.

The study on protein-protein interactions is rapidly increasing; one of the most important findings of such study is the observation of hub proteins that play vital roles in all organisms. Identifying hub proteins may provide more information on essential proteins and lead to more efficient methods for their prediction. Here, we proposed a new network topological-based method for prediction of hub proteins in Saccharomyces cerevisiae (baker's yeast). The method, HP3NN (Hub Protein Prediction using Probabilistic Neural Network), has successfully predicts the hub proteins with accuracy of 95% (sensitivity of 1.0 and specificity of 0.89).

Published in:

Bioinformatics and Bioengineering (BIBE), 2011 IEEE 11th International Conference on

Date of Conference:

24-26 Oct. 2011

Need Help?

IEEE Advancing Technology for Humanity About IEEE Xplore | Contact | Help | Terms of Use | Nondiscrimination Policy | Site Map | Privacy & Opting Out of Cookies

A not-for-profit organization, IEEE is the world's largest professional association for the advancement of technology.
© Copyright 2014 IEEE - All rights reserved. Use of this web site signifies your agreement to the terms and conditions.