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Portable and cost-effective pixel super-resolution on-chip microscope for telemedicine applications

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7 Author(s)
Bishara, W. ; Dept. of Electr. Eng., Univ. of California, Los Angeles, CA, USA ; Sikora, U. ; Mudanyali, O. ; Ting-Wei Su
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We report a field-portable lensless on-chip microscope with a lateral resolution of <;1μm and a large field-of-view of ~24mm2. This microscope is based on digital in-line holography and a pixel super-resolution algorithm to process multiple lensfree holograms and obtain a single high-resolution hologram. In its compact and cost-effective design, we utilize 23 light emitting diodes butt-coupled to 23 multi-mode optical fibers, and a simple optical filter, with no moving parts. Weighing only ~95 grams, we demonstrate the performance of this field-portable microscope by imaging various objects including human malaria parasites in thin blood smears.

Published in:

Engineering in Medicine and Biology Society, EMBC, 2011 Annual International Conference of the IEEE

Date of Conference:

Aug. 30 2011-Sept. 3 2011