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In this paper, we propose a memristor bridge circuit consisting of four identical memristors that is able to perform zero, negative, and positive synaptic weightings. Together with three additional transistors, the memristor bridge weighting circuit is able to perform synaptic operation for neural cells. It is compact as both weighting and weight programming are performed in a memristor bridge synapse. It is power efficient, since the operation is based on pulsed input signals. Its input terminals are utilized commonly for applying both weight programming and weight processing signals via time sharing. In this paper, features of the memristor bridge synapses are investigated using the TiO memristor model via simulations.