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This study examined the associations between coping styles and the outcomes of cancer treatments. In-person interviews were performed for the patients with stomach cancer. For three subscale scores of MCMQ, their partial correlation coefficients with patients' side effects of treatments were 0.042 (P=0.163) for confrontation, -0.007 (P=0.803) for avoidance, and 0.142 (P<;0.0001) for acceptance-resignation, respectively, with depression status were -0.069 (P=0.021), -0.027 (P=0.364), and 0.371 (P<;0.0001), respectively, and with total score of EORTC QLQ-C30 were 0.065 (P=0.555), 0.258 (P=0.018), and -0.275 (P=0.011), respectively. Confrontation and avoidance were not associated with performance status (P>;0.05), and the patients with poor performance status had the highest mean sore of acceptance-resignation (P<;0.05). Coping strategies play an important role in the outcome of cancer treatments. The patients adopted acceptance-resignation frequently have more severe side effects of cancer treatment, higher probability of suffering from depression, poor performance status, and poor quality of life.