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Ubiquitous Healthcare utilizes an array of small low-power environmental sensors for prognosis and diagnosis of health degradation. By focusing on condition-based monitoring of patient behavior and the ambient environment assessment, this paper presents a framework for syndromic surveillance of chronic disease with an emphasis on asthma and control using ubiquitous telemedicine solution. This allows regulation of indoor air quality for a healthy living environment for active prevention and provides a framework for automatic update of electronic patient record. Upon detection of any abnormality, the system can also trigger an alert for immediate medical attention to be provided.