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BAN(Body Area Network) has been researched widely in the world. The paper proposes the design of physiological information collection nodes based on wireless body area networks. This kind of node can not only collect blood oxygen and temperature but carry out wireless network transmission. The node adopts low energy consumption design. In order to save energy effectively, MSP 430 of TI Company is used to complete data transmission and CC2430 is adopted to achieve RF transmission. TDMA is used to complete data transmission, using the central node to send time slot number to every node, which, after synchronizing with the central control system, carries out data transmission only on its own time slot so as to avoid data conflict effectively.