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Health Information Systems (HIS) has become more complex and complicate to manage and maintain their secure operations. Many kinds of information security breaches and unintended information disclosures of confidential patient information have reported to warn the important security issues of HIS. Integrating of security considerations for developing complex HIS is emergent to provide a secure system for patients. While system architecture plays an important role in system development, we proposed an approach to enhance secure client-server system architecture for the development of HIS. After applying our approach, the satisfaction of security requirements in architecture can be checked by software and be reported quickly. Architects can modify the architecture to satisfy the corresponding security requirements with the reported descriptions and suggestion.