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Microfluidic surface-enhanced raman scattering sensors for online monitoring trace chemical mixing and reaction

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3 Author(s)
Mao, H.Y. ; Nat. Key Lab. of Sci. & Technol. on Micro/Nano Fabrication, Peking Univ., Beijing, China ; Lv, P.P. ; Wu, W.G.

We report a microfluidic surface-enhanced Raman scattering (SERS) sensor for online monitoring the mixing and reaction between chemicals of low concentration. The SERS sensor is made up of a SERS-active substrate and a polydimethylsiloxane cap with microchannels for delivering solutions. The SERS substrate consists of noble-metal covered silicon nanopillar-forest patterns, which are fabricated based on an oxygen-plasma-treating-on-photoresist technique. Enhancement factor of the device is self-calibrated to be on the order of 5.2×105, by utilizing the flat-metal areas beside the nanopillar-forest patterns as references. The mixing process of Crystal Violet and Rhodamine 6G trace solutions is characterized in the SERS sensor online and in real-time. Other kinetic features, including flow and diffusion, are also revealed.

Published in:
Solid-State Sensors, Actuators and Microsystems Conference (TRANSDUCERS), 2011 16th International

Date of Conference: 5-9 June 2011

Page(s):
1970 - 1973
ISSN :
Pending
Print ISBN:
978-1-4577-0157-3
INSPEC Accession Number:
12169396
Conference Location :
Beijing
Digital Object Identifier :
10.1109/TRANSDUCERS.2011.5969273
Product Type:
Conference Publications

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