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Patient self-management is an important component in improving quality of chronic disease healthcare. The promising benefits of the Interactive Behavior Change Technology (IBCT) on diabetes patient self-management are increasingly recognized. In this paper, we describe a service framework and two service systems designed to support self-care activities among type-2 diabetes patients: an automated telephone disease management (ATDM) service and a patient self-management support portal. In chronic disease healthcare, enhancing patients' self-management can lead to enhancing user-co-creation and participation in the service system. The services to support patients' self-management must also focus on user customization, i.e. personalization, of the services. We describe a personalized service framework that coordinates the related data, knowledge, interactions and personalized services in facilitating patients' self-care. Finally, we discuss potentials of the proposed service systems to provide supplements and add-values to conventional healthcare service.