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Long period grating-based fiber optic sensor for label-free DNA detection

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9 Author(s)
Sozzi, M. ; Inf. Eng. Dept., Univ. of Parma, Parma, Italy ; Coscelli, E. ; Poli, F. ; Cucinotta, A.
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The feasibility of a DNA biosensor based on a long period grating inscribed in an optical fiber has been investigated. The sensor can perform a label-free detection, due to the functionalization of the optical fiber external surface with peptide nucleic acid probes matched with the DNA target strands. A wavelength shift of 1.2 nm for a 120 nM DNA solution has been measured. Fluorescence measurements have been also taken, in order to give a further proof of the fiber functionalization and hybridization.

Published in:

BioPhotonics, 2011 International Workshop on

Date of Conference:

8-10 June 2011