By Topic

Regenerative microchannel electrode array for peripheral nerve interfacing

Sign In

Cookies must be enabled to login.After enabling cookies , please use refresh or reload or ctrl+f5 on the browser for the login options.

Formats Non-Member Member
$31 $13
Learn how you can qualify for the best price for this item!
Become an IEEE Member or Subscribe to
IEEE Xplore for exclusive pricing!
close button

puzzle piece

IEEE membership options for an individual and IEEE Xplore subscriptions for an organization offer the most affordable access to essential journal articles, conference papers, standards, eBooks, and eLearning courses.

Learn more about:

IEEE membership

IEEE Xplore subscriptions

3 Author(s)
Srinivasan, A. ; Wallace H. Coulter Dept. of Biomed. Eng., Emory Univ., Atlanta, GA, USA ; Liang Guo ; Bellamkonda, R.V.

A regenerative microchannel scaffold capable of housing microelectrodes to form a high-throughput peripheral nerve interface is described. The regenerative microchannel scaffold was fabricated using polydimethylsiloxane (PDMS) and SU-8 as substrate and structural materials, respectively. This microchannel scaffold is capable of being integrated with a PDMS-based thin-film microelectrode array (MEA) to form a peripheral nerve interface. Preliminary in vitro characterization was performed using dorsal root ganglia cultures to evaluate biocompatibility and the ability of the microchannel design to direct and orient neurite outgrowth. Our findings provided evidence that the microchannel design will be effective in directing axon regeneration to the benefit of a neural interfacing device.

Published in:

Neural Engineering (NER), 2011 5th International IEEE/EMBS Conference on

Date of Conference:

April 27 2011-May 1 2011