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With the fast growing population and urbanization in China, domestic waste management has become a great challenge. The challenge calls for more effective, efficient and more environmental friendly solutions to waste management. As a result, this study conducted a pilot plant test using origin-microbial bacterial technology and later applied the technology to purify septic tanks in the Meishanyuan district. In the study, the three compartments of each septic tank were used for the analysis. The results show that the average removal rates in the septic tanks for COD, total phosphorus and total nitrogen were 88.8%, 74.5% and 67.3% respectively after the pilot test. It was also revealed that the average removal rate of COD was higher than 80%, and more than 70% for total phosphorus and total nitrogen in the nineteen (19) selected septic tanks in the Meishanyuan district. The presence of fecal coliform in the resulting output was nearly non-existent, and the surface sludge in both second and third compartments were also significantly removed. Therefore, this technology without any large-scale renovation of existing systems proves to provide vital prospects for restoring water quality reliably and faster for the district. The technology is also cost-effective, and has the added value of saving energy, resource reusing and better economic and environmental benefits.