Cart (Loading....) | Create Account
Close category search window
 

Optical resolution of racemic compounds by chiral HPLC on immobilized amylose derivatives with regioselective substituents

Sign In

Cookies must be enabled to login.After enabling cookies , please use refresh or reload or ctrl+f5 on the browser for the login options.

Formats Non-Member Member
$31 $13
Learn how you can qualify for the best price for this item!
Become an IEEE Member or Subscribe to
IEEE Xplore for exclusive pricing!
close button

puzzle piece

IEEE membership options for an individual and IEEE Xplore subscriptions for an organization offer the most affordable access to essential journal articles, conference papers, standards, eBooks, and eLearning courses.

Learn more about:

IEEE membership

IEEE Xplore subscriptions

5 Author(s)
Jun Shen ; Coll. of Mater. Sci. & Chem. Eng., Harbin Eng. Univ., Harbin, China ; Shuangyan Liu ; Pengfei Li ; Xiande Shen
more authors

The optical resolution of various racemic compounds are evaluated by high-performance liquid chromatography (HPLC) using a new series of immobilized amylose derivatives as the chiral stationary phases (CSPs), which regioselectively carry two different substituents at 2-position and 3-, 6-positions. Each derivative exhibited its own characteristic recognition ability depending on the arrangement of side chains at different positions, indicating an attractive potential for the development of chiral drug industry. Some racemates can be efficiently separated on these derivatives as well as on the immobilized amylose tris(3,5-dimethylphenylcarbamate)s, which is commercially available as Chiralpak IA and one of the most powerful CSPs.

Published in:

Complex Medical Engineering (CME), 2011 IEEE/ICME International Conference on

Date of Conference:

22-25 May 2011

Need Help?


IEEE Advancing Technology for Humanity About IEEE Xplore | Contact | Help | Terms of Use | Nondiscrimination Policy | Site Map | Privacy & Opting Out of Cookies

A not-for-profit organization, IEEE is the world's largest professional association for the advancement of technology.
© Copyright 2014 IEEE - All rights reserved. Use of this web site signifies your agreement to the terms and conditions.