Cart (Loading....) | Create Account
Close category search window
 

Comparison of image Signal-to-Noise Ratio and Noise Equivalent Counts in Time-of-Flight PET

Sign In

Cookies must be enabled to login.After enabling cookies , please use refresh or reload or ctrl+f5 on the browser for the login options.

Formats Non-Member Member
$31 $13
Learn how you can qualify for the best price for this item!
Become an IEEE Member or Subscribe to
IEEE Xplore for exclusive pricing!
close button

puzzle piece

IEEE membership options for an individual and IEEE Xplore subscriptions for an organization offer the most affordable access to essential journal articles, conference papers, standards, eBooks, and eLearning courses.

Learn more about:

IEEE membership

IEEE Xplore subscriptions

4 Author(s)
Clementel, E. ; MEDISIP - IBBT, Univ. of Ghent, Ghent, Belgium ; Vandenberghe, S. ; Karp, J.S. ; Surti, S.

In PET imaging, Noise Equivalent Counts (NEC) represents an estimate of the number of true coincidences necessary in an ideal system to reach the Signal-to-Noise Ratio (SNR) obtained in a real system in the presence of scatter and random coincidences. NEC has been shown to be proportional to the square of image SNR and it is used as an index of the general system performance for conventional PET images. As clinical Time-of-Flight (TOF) PET scanners are now available from all major camera manufacturers, the original NEC formula does not directly account for the contribution of TOF timing resolution to the image SNR. This study measures SNR in images of a uniform phantom for TOF and Non-TOF PET at different NEC levels to study the relationship between SNR and NEC. A cylindrical uniform phantom, 20 cm in diameter was scanned covering a range of activity levels on a Philips Gemini TF scanner. From the original scans, at each activity level, a set of data realizations were obtained through bootstrapping. NEC is calculated from the original datasets using both the original NEMA formula and alternative formulas that include the TOF gain. SNR is calculated from the bootstrapped images, reconstructed with both TOF and Non-TOF algorithms and the relationship between SNR and NEC is investigated. The results show an appreciable gain in SNR obtained by using TOF information, and a correspondence between the region where NEC and SNR peaks occur. The relationship between the two quantities, however, is not clearly established and future studies including finer sampling on the acquisition of larger phantoms and simulations are needed.

Published in:

Nuclear Science Symposium Conference Record (NSS/MIC), 2010 IEEE

Date of Conference:

Oct. 30 2010-Nov. 6 2010

Need Help?


IEEE Advancing Technology for Humanity About IEEE Xplore | Contact | Help | Terms of Use | Nondiscrimination Policy | Site Map | Privacy & Opting Out of Cookies

A not-for-profit organization, IEEE is the world's largest professional association for the advancement of technology.
© Copyright 2014 IEEE - All rights reserved. Use of this web site signifies your agreement to the terms and conditions.