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Effects of Atrazine on Potassium Currents of Cortical Neurons of Rats

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5 Author(s)
Weiwei Zhang ; Sch. of Basic Med. Sci., HeBei Univ., Baoding, China ; Shumei Mu ; Xinwei Wang ; Xiaoqing Yu
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As a widely used herbicide, atrazine has various ecological and physiological toxicity, thus long-term exposure to the environment containing the herbicide will certainly affect the functions of different bio-organisms. K+ channel widely exists in animals and plays a significant role in keeping the excitability of neurons. In this study, whole cell patch-clamp recording was used to investigate the effects of atrazine treatment in different concentrations for different time on K+ currents of cultured cortical neurons from rats. The results indicated that the K+ currents were inhibited by atrazine treatment in a dose dependent manner in cortical neurons of rats.

Published in:
Bioinformatics and Biomedical Engineering, (iCBBE) 2011 5th International Conference on

Date of Conference: 10-12 May 2011

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