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Notice of Retraction
A Comparative Investigation of the Nitrosodimethylamine Formation from the Nitrosation of Dimethylamine and Trimethylamine by Nitrite under the Neutral Condition

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3 Author(s)
Qing-ming Liu ; Coll. of Life Sci. & Bioeng., Beijing Univ. of Technol., Beijing, China ; Yong Dong Liu ; Ru-gang Zhong

Notice of Retraction

After careful and considered review of the content of this paper by a duly constituted expert committee, this paper has been found to be in violation of IEEE's Publication Principles.

We hereby retract the content of this paper. Reasonable effort should be made to remove all past references to this paper.

The presenting author of this paper has the option to appeal this decision by contacting

The nitrosation reactions of dimethylamine (DMA) and trimethylamine (TMA) by nitrite to form carcinogenic nitrosodimethylamine (NDMA) were studied under the neutral condition. A comparative investigation of the amounts of NDMA formation from the nitrosation reaction of amines (DMA and TMA) by nitrite at various ratios of amine and nitrite in phosphate salt buffer (pH=6.4) at elevated temperature (90°C) was made. The results showed that, as varying the concentration of amine, the yields of NDMA from DMA are considerably higher than those from TMA when the ratio of amine to NO2- is in a range of 1:1 to 10:1, whereas the amounts of NDMA produced from TMA are obviously more than those from TMA when the ratio grows to 50:1 or more. Differently, as varying the concentration of nitrite, the amounts of NDMA formation from DMA are always more than from TMA when the ratio of nitrite to amine is in the range of 1:1 to 150:1.

Published in:

Bioinformatics and Biomedical Engineering, (iCBBE) 2011 5th International Conference on

Date of Conference:

10-12 May 2011