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Currently Internet of Things (IoT) and multimedia technologies have entered the healthcare field through ambient aiding living and telemedicine. However there are still several obstacles blocking in the way, the toughest ones among which are IoT interoperability, system security, streaming Quality of Service (QoS) and dynamic increasing storage. The major contribution of this paper is proposing an open, secure and flexible platform based on IoT and Cloud computing, on which several mainstream short distant ambient communication protocols for medical purpose are discussed to address interoperability; Secure Sockets Layer (SSL), authentication and auditing are taken into consideration to solve the security issue; an adaptive streaming QoS model is utilized to improve streaming quality in dynamic environment; and an open Cloud computing infrastructure is adopted to support elastic Electronic Health Record (EHR) archiving in the backend. Finally an integrated reference implementation is introduced to demonstrate feasibility.