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In this paper a low-power low-noise amplifier for neural recording and biomedical applications is presented. The frequency band of the amplifier is tunable. It has a gain of 28.3 dB. The low and the high cut-off frequency can be adjusted from 24 mHz to 30.6 Hz and 4.5 kHz to 7.47 kHz, respectively. The circuit is designed in 0.18μm CMOS process, and it consumes only 77.8 nW at 1.8V supply voltage. The simulation results show a 14.3μV input-referred noise corresponding to 1.32 efficiency factor (NEF). It is a great improvement compared with recent presented works in terms on power consumption and NEF which is vital in neural recording applications.