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Industrial symbiosis activities are being implemented in the philosophy of "circular economy" in China. Integrating industrial symbiosis into the corporate development plans to optimize materials and energy flows is a feasible strategy for many corporations in their transition between nonsustainable and sustainable development. The Beijiang Power Plant complex is the largest circular economy pilot in China. This study expounds on its transition course, and in which three factors are essential to making this symbiosis achievable: integration guiding principle; enterprises take the initiative; advanced technology support. We hope to point to a feasible development path for similar corporations.