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Dual-molecule spectroscopy: molecular rulers for the study of biological macromolecules

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4 Author(s)
Ha, T. ; Div. of Mater. Sci., Lawrence Berkeley Lab., CA, USA ; Enderle, Th. ; Chemla, D.S. ; Weiss, S.

Single-molecule detection and spectroscopy by laser induced fluorescence offer many applications to life sciences. We review recent techniques and experiments based on the detection and spectroscopy of two near-by molecules. The spectroscopic signature of the light emitted from the two molecules can be used to measure the distance, orientation and relative dynamics between biological macromolecules

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Selected Topics in Quantum Electronics, IEEE Journal of  (Volume:2 ,  Issue: 4 )