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Skeletal muscle as an adaptive contractile biomaterial for cardiac assistance: Fundamental considerations

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2 Author(s)
Salmons, Stanley ; British Heart Foundation Skeletal Muscle Assist Research Group, Department of Human Anatomy and Cell Biology, P.O. Box 147, University of Liverpool, Liverpool, U.K. ; Jarvis, J.C.

Adult fast-twitch mammalian skeletal muscle can acquire a markedly increased resistance to fatigue if it is suitably conditioned by long-term stimulation [7]. This discovery has revived interest in the possibility of diverting skeletal muscle from its normal function to perform in a cardiac assist role. There are a number of ways in which we can try to harness the power of conditioned skeletal muscle for cardiac assistance [3,11]. In all cases, the goal is a level of partial assistance that restores a reasonable quality of life while improving, or at least preventing further deterioration in, the condition of the patient's own heart.

Published in:

Engineering in Medicine and Biology Society, 1992 14th Annual International Conference of the IEEE  (Volume:7 )

Date of Conference:

Oct. 29 1992-Nov. 1 1992

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