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This study reported the feasibility of flushing remediation of lead (Pb) contaminated soil using thiacalixarenetetrasulfonate (TCAS) reagent. Batch experiments were performed to test the factors influencing remediation of lead (Pb) contaminated soil. The effects of pH value, initial conentration and contact time on the removal capacities of lead (Pb) by TCAS reagent had been studied. The results showed that the TCAS reagent was effective for removal of lead (Pb) from the contaminated soil, the optimum TCAS concentration is 0.7% for soil treatment, attaining 93.2% of lead (Pb) in the pH range of 11.0 within 24h.